Tanja Dominko

 Tanja DominkoOur lab investigates the molecular basis of stem cell gene activation in human fibroblasts during induced regeneration competence. We evaluate the role of FGF2 isoforms independently and in combination in order to identify key molecular mechanisms and pathways. We investigate FGF2 targets and partners during this phenotypic change.  Last, we investigate the role of low O2-induced chromatin modifiers JMJD histone demethylases in activation, and the maintenance of this FGF2-induced regeneration competent cell phenotype.



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